Neuropathic Pain - Bryn Thomas

Neuropathic pain is pain caused by a dysfunction in the nervous system.

Neuropathic pain may be caused by disorder of the central nervous system or the peripheral nervous system. Therefore the pain can be central, peripheral or mixed neuropathic pain.

Central neuropathic pain can be caused by spinal cord injuries, multiple sclerosis and sometimes in strokes.

Peripheral neuropathic pain can be caused by diabetes, herpes zoster or shingles, nutritional deficiencies, toxins, genetic and immunity disorders.

Neuropathic pain can be described as hot or cold, as a "pins and needles" sensation, numbness or itching. This is because neuropathic pain is caused by the firing of nerve fibres as well as other sensory fibres such as temperature and touch. Other signs include pain when pressure (touching or brushing) is applied to the area.

References:
Neuropathic pain : A practical guide for the clinician
http://www.cmaj.ca/cgi/content/full/175/3/265

http://www.virtualcancercentre.com/diseases.asp?did=797#Clinical_Examination

http://www.medicinenet.com/neuropathic_pain/article.htm